diff --git a/esphome/components/substitutions/jinja.py b/esphome/components/substitutions/jinja.py
index c6e40a668d..e7164d8fff 100644
--- a/esphome/components/substitutions/jinja.py
+++ b/esphome/components/substitutions/jinja.py
@@ -1,9 +1,10 @@
+from ast import literal_eval
 import logging
 import math
 import re
 
 import jinja2 as jinja
-from jinja2.nativetypes import NativeEnvironment
+from jinja2.sandbox import SandboxedEnvironment
 
 TemplateError = jinja.TemplateError
 TemplateSyntaxError = jinja.TemplateSyntaxError
@@ -70,7 +71,7 @@ class Jinja:
     """
 
     def __init__(self, context_vars):
-        self.env = NativeEnvironment(
+        self.env = SandboxedEnvironment(
             trim_blocks=True,
             lstrip_blocks=True,
             block_start_string="<%",
@@ -90,6 +91,15 @@ class Jinja:
             **SAFE_GLOBAL_FUNCTIONS,
         }
 
+    def safe_eval(self, expr):
+        try:
+            result = literal_eval(expr)
+            if not isinstance(result, str):
+                return result
+        except (ValueError, SyntaxError, MemoryError, TypeError):
+            pass
+        return expr
+
     def expand(self, content_str):
         """
         Renders a string that may contain Jinja expressions or statements
@@ -106,7 +116,7 @@ class Jinja:
             override_vars = content_str.upvalues
         try:
             template = self.env.from_string(content_str)
-            result = template.render(override_vars)
+            result = self.safe_eval(template.render(override_vars))
             if isinstance(result, Undefined):
                 # This happens when the expression is simply an undefined variable. Jinja does not
                 # raise an exception, instead we get "Undefined".
diff --git a/tests/unit_tests/fixtures/substitutions/00-simple_var.approved.yaml b/tests/unit_tests/fixtures/substitutions/00-simple_var.approved.yaml
index c59975b2ae..795a788f62 100644
--- a/tests/unit_tests/fixtures/substitutions/00-simple_var.approved.yaml
+++ b/tests/unit_tests/fixtures/substitutions/00-simple_var.approved.yaml
@@ -5,6 +5,9 @@ substitutions:
   var21: '79'
   value: 33
   values: 44
+  position:
+    x: 79
+    y: 82
 
 esphome:
   name: test
@@ -26,3 +29,7 @@ test_list:
   - Literal $values ${are not substituted}
   - ["list $value", "${is not}", "${substituted}"]
   - {"$dictionary": "$value", "${is not}": "${substituted}"}
+  - |-
+    {{{ "x", "79"}, { "y", "82"}}}
+  - '{{{"AA"}}}'
+  - '"HELLO"'
diff --git a/tests/unit_tests/fixtures/substitutions/00-simple_var.input.yaml b/tests/unit_tests/fixtures/substitutions/00-simple_var.input.yaml
index 3b7e7a6b4e..722e116d36 100644
--- a/tests/unit_tests/fixtures/substitutions/00-simple_var.input.yaml
+++ b/tests/unit_tests/fixtures/substitutions/00-simple_var.input.yaml
@@ -8,6 +8,9 @@ substitutions:
   var21: "79"
   value: 33
   values: 44
+  position:
+    x: 79
+    y: 82
 
 test_list:
   - "$var1"
@@ -27,3 +30,7 @@ test_list:
   - !literal Literal $values ${are not substituted}
   - !literal ["list $value", "${is not}", "${substituted}"]
   - !literal {"$dictionary": "$value", "${is not}": "${substituted}"}
+  - |- # Test parsing things that look like a python set of sets when rendered:
+    {{{ "x", "${ position.x }"}, { "y", "${ position.y }"}}}
+  - ${ '{{{"AA"}}}' }
+  - ${ '"HELLO"' }