diff --git a/esphome/components/usb_host/usb_host_client.cpp b/esphome/components/usb_host/usb_host_client.cpp
index 5c8874861e..91d7af2898 100644
--- a/esphome/components/usb_host/usb_host_client.cpp
+++ b/esphome/components/usb_host/usb_host_client.cpp
@@ -428,8 +428,8 @@ static void transfer_callback(usb_transfer_t *xfer) {
     trq->callback(trq->status);
   }
 
-  // Release transfer slot immediately in USB task to prevent slot exhaustion
-  // This is critical for high-throughput transfers (e.g., USB UART at 115200 baud)
+  // Release transfer slot AFTER callback completes to prevent slot exhaustion
+  // The callback has finished accessing xfer->data_buffer, so it's safe to release
   // The release_trq() uses thread-safe atomic operations
   trq->client->release_trq(trq);
 }