diff --git a/esphome/components/adc/adc_sensor.cpp b/esphome/components/adc/adc_sensor.cpp
index 2d6b87c51a..18464940f2 100644
--- a/esphome/components/adc/adc_sensor.cpp
+++ b/esphome/components/adc/adc_sensor.cpp
@@ -19,7 +19,7 @@ ADC_MODE(ADC_VCC)
 #endif
 
 #ifdef USE_ZEPHYR
-static const struct adc_dt_spec adc_chan = ADC_DT_SPEC_GET_BY_IDX(DT_PATH(zephyr_user), 1);
+#include "hal/nrf_saadc.h"
 #endif
 
 namespace esphome {
@@ -95,15 +95,14 @@ extern "C"
 #endif
 
 #ifdef USE_ZEPHYR
-  adc_chan_ = &adc_chan;
-  if (!adc_is_ready_dt(adc_chan_)) {
-    ESP_LOGE(TAG, "ADC controller device %s not ready", adc_chan_->dev->name);
+  if (!adc_is_ready_dt(adc_channel_)) {
+    ESP_LOGE(TAG, "ADC controller device %s not ready", adc_channel_->dev->name);
     return;
   }
 
-  auto err = adc_channel_setup_dt(adc_chan_);
+  auto err = adc_channel_setup_dt(adc_channel_);
   if (err < 0) {
-    ESP_LOGE(TAG, "Could not setup channel %s (%d)", adc_chan_->dev->name, err);
+    ESP_LOGE(TAG, "Could not setup channel %s (%d)", adc_channel_->dev->name, err);
     return;
   }
 #endif
@@ -158,8 +157,110 @@ void ADCSensor::dump_config() {
 #endif  // USE_RP2040
 
 #ifdef USE_ZEPHYR
-  ESP_LOGCONFIG(TAG, "  Name: %s, channel_id: %d, vref_mv: %d, resolution %d, oversampling %d", adc_chan_->dev->name,
-                adc_chan_->channel_id, adc_chan_->vref_mv, adc_chan_->resolution, adc_chan_->oversampling);
+  ESP_LOGCONFIG(TAG, "  Name: %s, channel_id: %d, vref_mv: %d, resolution %d, oversampling %d", adc_channel_->dev->name,
+                adc_channel_->channel_id, adc_channel_->vref_mv, adc_channel_->resolution, adc_channel_->oversampling);
+
+  auto gain = [](enum adc_gain gain) {
+    switch (gain) {
+      case ADC_GAIN_1_6: /**< x 1/6. */
+        return "1/6";
+      case ADC_GAIN_1_5: /**< x 1/5. */
+        return "1/5";
+      case ADC_GAIN_1_4: /**< x 1/4. */
+        return "1/4";
+      case ADC_GAIN_1_3: /**< x 1/3. */
+        return "1/3";
+      case ADC_GAIN_2_5: /**< x 2/5. */
+        return "2/5";
+      case ADC_GAIN_1_2: /**< x 1/2. */
+        return "1/2";
+      case ADC_GAIN_2_3: /**< x 2/3. */
+        return "2/3";
+      case ADC_GAIN_4_5: /**< x 4/5. */
+        return "4/5";
+      case ADC_GAIN_1: /**< x 1. */
+        return "1";
+      case ADC_GAIN_2: /**< x 2. */
+        return "2";
+      case ADC_GAIN_3: /**< x 3. */
+        return "3";
+      case ADC_GAIN_4: /**< x 4. */
+        return "4";
+      case ADC_GAIN_6: /**< x 6. */
+        return "6";
+      case ADC_GAIN_8: /**< x 8. */
+        return "8";
+      case ADC_GAIN_12: /**< x 12. */
+        return "12";
+      case ADC_GAIN_16: /**< x 16. */
+        return "16";
+      case ADC_GAIN_24: /**< x 24. */
+        return "24";
+      case ADC_GAIN_32: /**< x 32. */
+        return "32";
+      case ADC_GAIN_64: /**< x 64. */
+        return "64";
+      case ADC_GAIN_128: /**< x 128. */
+        return "128";
+    }
+    return "undefined";
+  };
+
+  auto reference = [](enum adc_reference reference) {
+    switch (reference) {
+      case ADC_REF_VDD_1:
+        return "VDD";
+      case ADC_REF_VDD_1_2:
+        return "VDD/2";
+      case ADC_REF_VDD_1_3:
+        return "VDD/2";
+      case ADC_REF_VDD_1_4:
+        return "VDD/4";
+      case ADC_REF_INTERNAL:
+        return "INTERNAL";
+      case ADC_REF_EXTERNAL0:
+        return "External, input 0";
+      case ADC_REF_EXTERNAL1:
+        return "External, input 1";
+    }
+    return "undefined";
+  };
+
+  auto input = [](uint8_t input) {
+    switch (input) {
+      case NRF_SAADC_INPUT_AIN0:
+        return "AIN0";
+      case NRF_SAADC_INPUT_AIN1:
+        return "AIN1";
+      case NRF_SAADC_INPUT_AIN2:
+        return "AIN2";
+      case NRF_SAADC_INPUT_AIN3:
+        return "AIN3";
+      case NRF_SAADC_INPUT_AIN4:
+        return "AIN4";
+      case NRF_SAADC_INPUT_AIN5:
+        return "AIN5";
+      case NRF_SAADC_INPUT_AIN6:
+        return "AIN6";
+      case NRF_SAADC_INPUT_AIN7:
+        return "AIN7";
+      case NRF_SAADC_INPUT_VDD:
+        return "VDD";
+      case NRF_SAADC_INPUT_VDDHDIV5:
+        return "VDDHDIV5";
+    }
+    return "undefined";
+  };
+
+  ESP_LOGCONFIG(TAG, "  Gain: %s, reference: %s, acquisition_time: %d, differential %s",
+                gain(adc_channel_->channel_cfg.gain), reference(adc_channel_->channel_cfg.reference),
+                adc_channel_->channel_cfg.acquisition_time, YESNO(adc_channel_->channel_cfg.differential));
+  if (adc_channel_->channel_cfg.differential) {
+    ESP_LOGCONFIG(TAG, "  Input positive: %s, negative: %s", input(adc_channel_->channel_cfg.input_positive),
+                  input(adc_channel_->channel_cfg.input_negative));
+  } else {
+    ESP_LOGCONFIG(TAG, "  Input positive: %s", input(adc_channel_->channel_cfg.input_positive));
+  }
 #endif
 
   LOG_UPDATE_INTERVAL(this);
@@ -331,11 +432,11 @@ float ADCSensor::sample() {
   };
   int32_t val_mv;
 
-  adc_sequence_init_dt(adc_chan_, &sequence);
+  adc_sequence_init_dt(adc_channel_, &sequence);
 
-  auto err = adc_read(adc_chan_->dev, &sequence);
+  auto err = adc_read(adc_channel_->dev, &sequence);
   if (err < 0) {
-    ESP_LOGE(TAG, "Could not read %s (%d)", adc_chan_->dev->name, err);
+    ESP_LOGE(TAG, "Could not read %s (%d)", adc_channel_->dev->name, err);
     return 0.0;
   }
 
@@ -344,7 +445,7 @@ float ADCSensor::sample() {
    * in the ADC sample buffer should be a signed 2's
    * complement value.
    */
-  if (adc_chan_->channel_cfg.differential) {
+  if (adc_channel_->channel_cfg.differential) {
     val_mv = (int32_t) ((int16_t) buf);
   } else {
     val_mv = (int32_t) buf;
@@ -354,10 +455,10 @@ float ADCSensor::sample() {
     return val_mv;
   }
 
-  err = adc_raw_to_millivolts_dt(adc_chan_, &val_mv);
+  err = adc_raw_to_millivolts_dt(adc_channel_, &val_mv);
   /* conversion to mV may not be supported, skip if not */
   if (err < 0) {
-    ESP_LOGE(TAG, "Value in mV not available %s (%d)", adc_chan_->dev->name, err);
+    ESP_LOGE(TAG, "Value in mV not available %s (%d)", adc_channel_->dev->name, err);
     return 0.0;
   }
 
diff --git a/esphome/components/adc/adc_sensor.h b/esphome/components/adc/adc_sensor.h
index 0e58a6e423..7498d72902 100644
--- a/esphome/components/adc/adc_sensor.h
+++ b/esphome/components/adc/adc_sensor.h
@@ -42,6 +42,8 @@ class ADCSensor : public sensor::Sensor, public PollingComponent, public voltage
   float get_setup_priority() const override;
 #ifndef USE_ZEPHYR
   void set_pin(InternalGPIOPin *pin) { this->pin_ = pin; }
+#else
+  void set_adc_channel(const adc_dt_spec *adc_channel) { this->adc_channel_ = adc_channel; }
 #endif
   void set_output_raw(bool output_raw) { output_raw_ = output_raw; }
   float sample() override;
@@ -58,7 +60,7 @@ class ADCSensor : public sensor::Sensor, public PollingComponent, public voltage
 #ifndef USE_ZEPHYR
   InternalGPIOPin *pin_;
 #else
-  const struct adc_dt_spec *adc_chan_;
+  const struct adc_dt_spec *adc_channel_ = nullptr;
 #endif
   bool output_raw_{false};
 
diff --git a/esphome/components/adc/sensor.py b/esphome/components/adc/sensor.py
index df47731d69..1008706a8c 100644
--- a/esphome/components/adc/sensor.py
+++ b/esphome/components/adc/sensor.py
@@ -1,3 +1,4 @@
+from esphome.cpp_generator import MockObj
 import esphome.codegen as cg
 import esphome.config_validation as cv
 import esphome.final_validate as fv
@@ -56,6 +57,10 @@ ADCSensor = adc_ns.class_(
     "ADCSensor", sensor.Sensor, cg.PollingComponent, voltage_sampler.VoltageSampler
 )
 
+CONF_NRF_SAADC = "nrf_saadc"
+
+adc_dt_spec = cg.global_ns.class_("adc_dt_spec").operator("const")
+
 CONFIG_SCHEMA = cv.All(
     sensor.sensor_schema(
         ADCSensor,
@@ -71,6 +76,9 @@ CONFIG_SCHEMA = cv.All(
             cv.SplitDefault(CONF_ATTENUATION, esp32="0db"): cv.All(
                 cv.only_on_esp32, cv.enum(ATTENUATION_MODES, lower=True)
             ),
+            cv.GenerateID(CONF_NRF_SAADC): cv.All(
+                cv.only_on_nrf52, cv.declare_id(adc_dt_spec)
+            ),
         }
     )
     .extend(cv.polling_component_schema("60s")),
@@ -91,48 +99,36 @@ async def to_code(config):
         cg.add(var.set_is_temperature())
     elif CORE.using_zephyr:
         zephyr_add_prj_conf("ADC", True)
+        nrf_saadc = config[CONF_NRF_SAADC]
+        channel_id = int(str(nrf_saadc)[str(nrf_saadc).find("_id") + 4 :] or "1") - 1
+        rhs = MockObj(f"ADC_DT_SPEC_GET_BY_IDX(DT_PATH(zephyr_user), {channel_id})")
+        adc = cg.new_Pvariable(nrf_saadc, rhs)
+        cg.add(var.set_adc_channel(adc))
+        gain = "ADC_GAIN_1_6"
         zephyr_add_overlay(
             """
 / {
     zephyr,user {
-        io-channels = <&adc 0>, <&adc 1>, <&adc 7>;
+        io-channels = <&adc 0>, <&adc 1>, <&adc 2>;
     };
-};
-
-&adc {
+};"""
+        )
+        zephyr_add_overlay(
+            f"""
+&adc {{
     #address-cells = <1>;
     #size-cells = <0>;
 
-    channel@0 {
-        reg = <0>;
-        zephyr,gain = "ADC_GAIN_1_6";
+    channel@{channel_id} {{
+        reg = <{channel_id}>;
+        zephyr,gain = "{gain}";
         zephyr,reference = "ADC_REF_INTERNAL";
         zephyr,acquisition-time = <ADC_ACQ_TIME_DEFAULT>;
-        zephyr,input-positive = <NRF_SAADC_AIN1>; /* P0.03 */
-        zephyr,resolution = <12>;
-    };
-
-    channel@1 {
-        reg = <1>;
-        zephyr,gain = "ADC_GAIN_1_6";
-        zephyr,reference = "ADC_REF_INTERNAL";
-        zephyr,acquisition-time = <ADC_ACQ_TIME_DEFAULT>;
-        zephyr,input-positive = <NRF_SAADC_VDD>;
+        zephyr,input-positive = <NRF_SAADC_{config[CONF_PIN][CONF_NUMBER]}>;
         zephyr,resolution = <14>;
         zephyr,oversampling = <8>;
-    };
-
-    channel@7 {
-        reg = <7>;
-        zephyr,gain = "ADC_GAIN_1_5";
-        zephyr,reference = "ADC_REF_VDD_1_4";
-        zephyr,vref-mv = <750>;
-        zephyr,acquisition-time = <ADC_ACQ_TIME_DEFAULT>;
-        zephyr,input-positive = <NRF_SAADC_AIN6>; /* P0.30 */
-        zephyr,input-negative = <NRF_SAADC_AIN7>; /* P0.31 */
-        zephyr,resolution = <12>;
-    };
-};
+    }};
+}};
 """
         )
     else:
diff --git a/esphome/components/nrf52/gpio.py b/esphome/components/nrf52/gpio.py
index 0271972f92..5b31d63b57 100644
--- a/esphome/components/nrf52/gpio.py
+++ b/esphome/components/nrf52/gpio.py
@@ -46,7 +46,7 @@ ADC_INPUTS = [
     "AIN6",
     "AIN7",
     "VDD",
-    "VDDH",
+    "VDDHDIV5",
 ]
 
 
diff --git a/esphome/components/zephyr_ble_nus/ble_nus.h b/esphome/components/zephyr_ble_nus/ble_nus.h
index b08c3d102e..b980c36d1b 100644
--- a/esphome/components/zephyr_ble_nus/ble_nus.h
+++ b/esphome/components/zephyr_ble_nus/ble_nus.h
@@ -16,7 +16,7 @@ class BLENUS : public Component {
   };
 
  public:
-  BLENUS(size_t buffer_size = 1024);
+  BLENUS(size_t buffer_size = 2048);
   void setup() override;
   void dump_config() override;
   void loop() override;
diff --git a/tests/components/adc/test.nrf52-adafruit.yaml b/tests/components/adc/test.nrf52-adafruit.yaml
new file mode 100644
index 0000000000..4a83d173d5
--- /dev/null
+++ b/tests/components/adc/test.nrf52-adafruit.yaml
@@ -0,0 +1,18 @@
+sensor:
+  - platform: uptime
+    name: Uptime Sensor
+    update_interval: 5sec
+  - platform: adc
+    pin: VDDHDIV5
+    name: "VDDH Voltage"
+    update_interval: 5sec
+    filters:
+      - multiply: 5
+  - platform: adc
+    pin: VDD
+    name: "VDD Voltage"
+    update_interval: 5sec
+  - platform: adc
+    pin: AIN0
+    name: "AIN0 Voltage"
+    update_interval: 5sec
diff --git a/tests/components/adc/test.nrf52.yaml b/tests/components/adc/test.nrf52.yaml
new file mode 100644
index 0000000000..4a83d173d5
--- /dev/null
+++ b/tests/components/adc/test.nrf52.yaml
@@ -0,0 +1,18 @@
+sensor:
+  - platform: uptime
+    name: Uptime Sensor
+    update_interval: 5sec
+  - platform: adc
+    pin: VDDHDIV5
+    name: "VDDH Voltage"
+    update_interval: 5sec
+    filters:
+      - multiply: 5
+  - platform: adc
+    pin: VDD
+    name: "VDD Voltage"
+    update_interval: 5sec
+  - platform: adc
+    pin: AIN0
+    name: "AIN0 Voltage"
+    update_interval: 5sec
diff --git a/tests/components/uptime/test.nrf52-adafruit.yaml b/tests/components/uptime/test.nrf52-adafruit.yaml
new file mode 100644
index 0000000000..dade44d145
--- /dev/null
+++ b/tests/components/uptime/test.nrf52-adafruit.yaml
@@ -0,0 +1 @@
+<<: !include common.yaml
diff --git a/tests/components/uptime/test.nrf52.yaml b/tests/components/uptime/test.nrf52.yaml
new file mode 100644
index 0000000000..dade44d145
--- /dev/null
+++ b/tests/components/uptime/test.nrf52.yaml
@@ -0,0 +1 @@
+<<: !include common.yaml
diff --git a/tests/test12.2.yaml b/tests/test12.2.yaml
index f2bb074fdc..cb4dbe3b0e 100644
--- a/tests/test12.2.yaml
+++ b/tests/test12.2.yaml
@@ -80,10 +80,15 @@ zephyr_debug:
 debug:
 
 sensor:
+  - platform: uptime
+    name: Uptime Sensor
+    update_interval: 5sec
   - platform: adc
-    pin: VDDH
+    pin: VDDHDIV5
     name: "VDDH Voltage"
     update_interval: 5sec
+    filters:
+      - multiply: 5
   - platform: adc
     pin: VDD
     name: "VDD Voltage"
diff --git a/tests/test12.3.yaml b/tests/test12.3.yaml
index fb26628820..9cc5b6997b 100644
--- a/tests/test12.3.yaml
+++ b/tests/test12.3.yaml
@@ -45,9 +45,21 @@ zephyr_debug:
 
 debug:
 
-text_sensor:
-  - platform: debug
-    device:
-      name: "Device Info"
-    reset_reason:
-      name: "Reset Reason"
+sensor:
+  - platform: uptime
+    name: Uptime Sensor
+    update_interval: 5sec
+  - platform: adc
+    pin: VDDHDIV5
+    name: "VDDH Voltage"
+    update_interval: 5sec
+    filters:
+      - multiply: 5
+  - platform: adc
+    pin: VDD
+    name: "VDD Voltage"
+    update_interval: 5sec
+  - platform: adc
+    pin: AIN0
+    name: "AIN0 Voltage"
+    update_interval: 5sec