diff --git a/CODEOWNERS b/CODEOWNERS
index 82aa071dc4..5a8ef76c44 100644
--- a/CODEOWNERS
+++ b/CODEOWNERS
@@ -188,6 +188,7 @@ esphome/components/nfc/* @jesserockz
 esphome/components/number/* @esphome/core
 esphome/components/ota/* @esphome/core
 esphome/components/output/* @esphome/core
+esphome/components/pca6416a/* @Mat931
 esphome/components/pca9554/* @hwstar
 esphome/components/pcf85063/* @brogon
 esphome/components/pid/* @OttoWinter
diff --git a/esphome/components/pca6416a/__init__.py b/esphome/components/pca6416a/__init__.py
new file mode 100644
index 0000000000..574d8dce91
--- /dev/null
+++ b/esphome/components/pca6416a/__init__.py
@@ -0,0 +1,78 @@
+import esphome.codegen as cg
+import esphome.config_validation as cv
+from esphome import pins
+from esphome.components import i2c
+from esphome.const import (
+    CONF_ID,
+    CONF_INPUT,
+    CONF_NUMBER,
+    CONF_MODE,
+    CONF_INVERTED,
+    CONF_OUTPUT,
+    CONF_PULLUP,
+)
+
+CODEOWNERS = ["@Mat931"]
+DEPENDENCIES = ["i2c"]
+MULTI_CONF = True
+pca6416a_ns = cg.esphome_ns.namespace("pca6416a")
+
+PCA6416AComponent = pca6416a_ns.class_("PCA6416AComponent", cg.Component, i2c.I2CDevice)
+PCA6416AGPIOPin = pca6416a_ns.class_(
+    "PCA6416AGPIOPin", cg.GPIOPin, cg.Parented.template(PCA6416AComponent)
+)
+
+CONF_PCA6416A = "pca6416a"
+CONFIG_SCHEMA = (
+    cv.Schema({cv.Required(CONF_ID): cv.declare_id(PCA6416AComponent)})
+    .extend(cv.COMPONENT_SCHEMA)
+    .extend(i2c.i2c_device_schema(0x21))
+)
+
+
+async def to_code(config):
+    var = cg.new_Pvariable(config[CONF_ID])
+    await cg.register_component(var, config)
+    await i2c.register_i2c_device(var, config)
+
+
+def validate_mode(value):
+    if not (value[CONF_INPUT] or value[CONF_OUTPUT]):
+        raise cv.Invalid("Mode must be either input or output")
+    if value[CONF_INPUT] and value[CONF_OUTPUT]:
+        raise cv.Invalid("Mode must be either input or output")
+    if value[CONF_PULLUP] and not value[CONF_INPUT]:
+        raise cv.Invalid("Pullup only available with input")
+    return value
+
+
+PCA6416A_PIN_SCHEMA = cv.All(
+    {
+        cv.GenerateID(): cv.declare_id(PCA6416AGPIOPin),
+        cv.Required(CONF_PCA6416A): cv.use_id(PCA6416AComponent),
+        cv.Required(CONF_NUMBER): cv.int_range(min=0, max=16),
+        cv.Optional(CONF_MODE, default={}): cv.All(
+            {
+                cv.Optional(CONF_INPUT, default=False): cv.boolean,
+                cv.Optional(CONF_PULLUP, default=False): cv.boolean,
+                cv.Optional(CONF_OUTPUT, default=False): cv.boolean,
+            },
+            validate_mode,
+        ),
+        cv.Optional(CONF_INVERTED, default=False): cv.boolean,
+    }
+)
+
+
+@pins.PIN_SCHEMA_REGISTRY.register("pca6416a", PCA6416A_PIN_SCHEMA)
+async def pca6416a_pin_to_code(config):
+    var = cg.new_Pvariable(config[CONF_ID])
+    parent = await cg.get_variable(config[CONF_PCA6416A])
+
+    cg.add(var.set_parent(parent))
+
+    num = config[CONF_NUMBER]
+    cg.add(var.set_pin(num))
+    cg.add(var.set_inverted(config[CONF_INVERTED]))
+    cg.add(var.set_flags(pins.gpio_flags_expr(config[CONF_MODE])))
+    return var
diff --git a/esphome/components/pca6416a/pca6416a.cpp b/esphome/components/pca6416a/pca6416a.cpp
new file mode 100644
index 0000000000..1f4e315644
--- /dev/null
+++ b/esphome/components/pca6416a/pca6416a.cpp
@@ -0,0 +1,174 @@
+#include "pca6416a.h"
+#include "esphome/core/log.h"
+
+namespace esphome {
+namespace pca6416a {
+
+enum PCA6416AGPIORegisters {
+  // 0 side
+  PCA6416A_INPUT0 = 0x00,
+  PCA6416A_OUTPUT0 = 0x02,
+  PCA6416A_INVERT0 = 0x04,
+  PCA6416A_CONFIG0 = 0x06,
+  PCAL6416A_PULL_EN0 = 0x46,
+  PCAL6416A_PULL_DIR0 = 0x48,
+  // 1 side
+  PCA6416A_INPUT1 = 0x01,
+  PCA6416A_OUTPUT1 = 0x03,
+  PCA6416A_INVERT1 = 0x05,
+  PCA6416A_CONFIG1 = 0x07,
+  PCAL6416A_PULL_EN1 = 0x47,
+  PCAL6416A_PULL_DIR1 = 0x49,
+};
+
+static const char *const TAG = "pca6416a";
+
+void PCA6416AComponent::setup() {
+  ESP_LOGCONFIG(TAG, "Setting up PCA6416A...");
+  // Test to see if device exists
+  uint8_t value;
+  if (!this->read_register_(PCA6416A_INPUT0, &value)) {
+    ESP_LOGE(TAG, "PCA6416A not available under 0x%02X", this->address_);
+    this->mark_failed();
+    return;
+  }
+
+  // Test to see if the device supports pull-up resistors
+  if (this->read_register(PCAL6416A_PULL_EN0, &value, 1, true) == esphome::i2c::ERROR_OK) {
+    this->has_pullup_ = true;
+  }
+
+  // No polarity inversion
+  this->write_register_(PCA6416A_INVERT0, 0);
+  this->write_register_(PCA6416A_INVERT1, 0);
+  // Set all pins to input
+  this->write_register_(PCA6416A_CONFIG0, 0xff);
+  this->write_register_(PCA6416A_CONFIG1, 0xff);
+  // Read current output register state
+  this->read_register_(PCA6416A_OUTPUT0, &this->output_0_);
+  this->read_register_(PCA6416A_OUTPUT1, &this->output_1_);
+
+  ESP_LOGD(TAG, "Initialization complete. Warning: %d, Error: %d", this->status_has_warning(),
+           this->status_has_error());
+}
+
+void PCA6416AComponent::dump_config() {
+  if (this->has_pullup_) {
+    ESP_LOGCONFIG(TAG, "PCAL6416A:");
+  } else {
+    ESP_LOGCONFIG(TAG, "PCA6416A:");
+  }
+  LOG_I2C_DEVICE(this)
+  if (this->is_failed()) {
+    ESP_LOGE(TAG, "Communication with PCA6416A failed!");
+  }
+}
+
+bool PCA6416AComponent::digital_read(uint8_t pin) {
+  uint8_t bit = pin % 8;
+  uint8_t reg_addr = pin < 8 ? PCA6416A_INPUT0 : PCA6416A_INPUT1;
+  uint8_t value = 0;
+  this->read_register_(reg_addr, &value);
+  return value & (1 << bit);
+}
+
+void PCA6416AComponent::digital_write(uint8_t pin, bool value) {
+  uint8_t reg_addr = pin < 8 ? PCA6416A_OUTPUT0 : PCA6416A_OUTPUT1;
+  this->update_register_(pin, value, reg_addr);
+}
+
+void PCA6416AComponent::pin_mode(uint8_t pin, gpio::Flags flags) {
+  uint8_t io_dir = pin < 8 ? PCA6416A_CONFIG0 : PCA6416A_CONFIG1;
+  uint8_t pull_en = pin < 8 ? PCAL6416A_PULL_EN0 : PCAL6416A_PULL_EN1;
+  uint8_t pull_dir = pin < 8 ? PCAL6416A_PULL_DIR0 : PCAL6416A_PULL_DIR1;
+  if (flags == gpio::FLAG_INPUT) {
+    this->update_register_(pin, true, io_dir);
+    if (has_pullup_) {
+      this->update_register_(pin, true, pull_dir);
+      this->update_register_(pin, false, pull_en);
+    }
+  } else if (flags == (gpio::FLAG_INPUT | gpio::FLAG_PULLUP)) {
+    this->update_register_(pin, true, io_dir);
+    if (has_pullup_) {
+      this->update_register_(pin, true, pull_dir);
+      this->update_register_(pin, true, pull_en);
+    } else {
+      ESP_LOGW(TAG, "Your PCA6416A does not support pull-up resistors");
+    }
+  } else if (flags == gpio::FLAG_OUTPUT) {
+    this->update_register_(pin, false, io_dir);
+  }
+}
+
+bool PCA6416AComponent::read_register_(uint8_t reg, uint8_t *value) {
+  if (this->is_failed()) {
+    ESP_LOGD(TAG, "Device marked failed");
+    return false;
+  }
+
+  if ((this->last_error_ = this->read_register(reg, value, 1, true)) != esphome::i2c::ERROR_OK) {
+    this->status_set_warning();
+    ESP_LOGE(TAG, "read_register_(): I2C I/O error: %d", (int) this->last_error_);
+    return false;
+  }
+
+  this->status_clear_warning();
+  return true;
+}
+
+bool PCA6416AComponent::write_register_(uint8_t reg, uint8_t value) {
+  if (this->is_failed()) {
+    ESP_LOGD(TAG, "Device marked failed");
+    return false;
+  }
+
+  if ((this->last_error_ = this->write_register(reg, &value, 1, true)) != esphome::i2c::ERROR_OK) {
+    this->status_set_warning();
+    ESP_LOGE(TAG, "write_register_(): I2C I/O error: %d", (int) this->last_error_);
+    return false;
+  }
+
+  this->status_clear_warning();
+  return true;
+}
+
+void PCA6416AComponent::update_register_(uint8_t pin, bool pin_value, uint8_t reg_addr) {
+  uint8_t bit = pin % 8;
+  uint8_t reg_value = 0;
+  if (reg_addr == PCA6416A_OUTPUT0) {
+    reg_value = this->output_0_;
+  } else if (reg_addr == PCA6416A_OUTPUT1) {
+    reg_value = this->output_1_;
+  } else {
+    this->read_register_(reg_addr, &reg_value);
+  }
+
+  if (pin_value) {
+    reg_value |= 1 << bit;
+  } else {
+    reg_value &= ~(1 << bit);
+  }
+
+  this->write_register_(reg_addr, reg_value);
+
+  if (reg_addr == PCA6416A_OUTPUT0) {
+    this->output_0_ = reg_value;
+  } else if (reg_addr == PCA6416A_OUTPUT1) {
+    this->output_1_ = reg_value;
+  }
+}
+
+float PCA6416AComponent::get_setup_priority() const { return setup_priority::IO; }
+
+void PCA6416AGPIOPin::setup() { pin_mode(flags_); }
+void PCA6416AGPIOPin::pin_mode(gpio::Flags flags) { this->parent_->pin_mode(this->pin_, flags); }
+bool PCA6416AGPIOPin::digital_read() { return this->parent_->digital_read(this->pin_) != this->inverted_; }
+void PCA6416AGPIOPin::digital_write(bool value) { this->parent_->digital_write(this->pin_, value != this->inverted_); }
+std::string PCA6416AGPIOPin::dump_summary() const {
+  char buffer[32];
+  snprintf(buffer, sizeof(buffer), "%u via PCA6416A", pin_);
+  return buffer;
+}
+
+}  // namespace pca6416a
+}  // namespace esphome
diff --git a/esphome/components/pca6416a/pca6416a.h b/esphome/components/pca6416a/pca6416a.h
new file mode 100644
index 0000000000..247f443e87
--- /dev/null
+++ b/esphome/components/pca6416a/pca6416a.h
@@ -0,0 +1,63 @@
+#pragma once
+
+#include "esphome/core/component.h"
+#include "esphome/core/hal.h"
+#include "esphome/components/i2c/i2c.h"
+
+namespace esphome {
+namespace pca6416a {
+
+class PCA6416AComponent : public Component, public i2c::I2CDevice {
+ public:
+  PCA6416AComponent() = default;
+
+  /// Check i2c availability and setup masks
+  void setup() override;
+  /// Helper function to read the value of a pin.
+  bool digital_read(uint8_t pin);
+  /// Helper function to write the value of a pin.
+  void digital_write(uint8_t pin, bool value);
+  /// Helper function to set the pin mode of a pin.
+  void pin_mode(uint8_t pin, gpio::Flags flags);
+
+  float get_setup_priority() const override;
+
+  void dump_config() override;
+
+ protected:
+  bool read_register_(uint8_t reg, uint8_t *value);
+  bool write_register_(uint8_t reg, uint8_t value);
+  void update_register_(uint8_t pin, bool pin_value, uint8_t reg_addr);
+
+  /// The mask to write as output state - 1 means HIGH, 0 means LOW
+  uint8_t output_0_{0x00};
+  uint8_t output_1_{0x00};
+  /// Storage for last I2C error seen
+  esphome::i2c::ErrorCode last_error_;
+  /// Only the PCAL6416A has pull-up resistors
+  bool has_pullup_{false};
+};
+
+/// Helper class to expose a PCA6416A pin as an internal input GPIO pin.
+class PCA6416AGPIOPin : public GPIOPin {
+ public:
+  void setup() override;
+  void pin_mode(gpio::Flags flags) override;
+  bool digital_read() override;
+  void digital_write(bool value) override;
+  std::string dump_summary() const override;
+
+  void set_parent(PCA6416AComponent *parent) { parent_ = parent; }
+  void set_pin(uint8_t pin) { pin_ = pin; }
+  void set_inverted(bool inverted) { inverted_ = inverted; }
+  void set_flags(gpio::Flags flags) { flags_ = flags; }
+
+ protected:
+  PCA6416AComponent *parent_;
+  uint8_t pin_;
+  bool inverted_;
+  gpio::Flags flags_;
+};
+
+}  // namespace pca6416a
+}  // namespace esphome
diff --git a/tests/test1.yaml b/tests/test1.yaml
index a235ff1502..c5cca7aa59 100644
--- a/tests/test1.yaml
+++ b/tests/test1.yaml
@@ -1449,6 +1449,13 @@ binary_sensor:
       number: 1
       mode: INPUT
       inverted: true
+  - platform: gpio
+    name: PCA6416A binary sensor
+    pin:
+      pca6416a: pca6416a_hub
+      number: 15
+      mode: INPUT
+      inverted: true
   - platform: gpio
     name: MCP21 binary sensor
     pin:
@@ -2934,6 +2941,11 @@ pca9554:
     address: 0x3F
     i2c_id: i2c_bus
 
+pca6416a:
+  - id: pca6416a_hub
+    address: 0x21
+    i2c_id: i2c_bus
+
 mcp23017:
   - id: mcp23017_hub
     open_drain_interrupt: true